For the following uses, polyplasdone crospovidone is the preferred disintegrant: When employed intragranularly, Polyplasdone XL-10 crospovidone's tiny average particle size facilitates quick disintegration in wet-granulation tablet processes.

  • Polyplasdone XL Type A
  • Polyplasdone XL 10 Type B
  • Polyplasdone INF 10 Type B
  • Polyplasdone Ultra Type A
  • Crospovidone ashland make

provides rapid disintegration in wet and dry granulation and direct compression tablet processes

combines multiple mechanisms to achieve disintegration at low use levels (2-5 wt%)

swells without forming gels that can slow tablet disintegration or dissolution

increases tablet breaking force and reduces friability

enhances the dissolution of poorly soluble drugs

available in Type A and Type B crospovidone grades

polyplasdone ultra and ultra-10 grades provide the same great performance with very low peroxide levels

applications

  • disintegration
  • drug solubilization
  • suspending agent