For the following uses, polyplasdone crospovidone is the preferred disintegrant: When employed intragranularly, Polyplasdone XL-10 crospovidone's tiny average particle size facilitates quick disintegration in wet-granulation tablet processes.
Polyplasdone XL Type A
Polyplasdone XL 10 Type B
Polyplasdone INF 10 Type B
Polyplasdone Ultra Type A
Crospovidone ashland make
provides rapid disintegration in wet and dry granulation and direct compression tablet processes
combines multiple mechanisms to achieve disintegration at low use levels (2-5 wt%)
swells without forming gels that can slow tablet disintegration or dissolution
increases tablet breaking force and reduces friability
enhances the dissolution of poorly soluble drugs
available in Type A and Type B crospovidone grades
polyplasdone ultra and ultra-10 grades provide the same great performance with very low peroxide levels
2026
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